![]() ![]() Recent technological advances have exponentially expanded the breadth of available -omics data, from genome, epigenome, transcriptome, proteome, metabolome to even the microbiome. It is likely that non-linear and complex interactions occur between these multiple factors, involving simultaneous pathological changes in diverse cell types, tissues, and organs, at multiple molecular levels. Genetic predisposition as well as the environment and lifestyle are thought to contribute to disease risk. 2Munich Heart Alliance, German Centre for Cardiovascular Research, Munich, GermanyĬoronary artery disease (CAD) and myocardial infarction (MI) remain among the leading causes of mortality worldwide, urgently demanding a better understanding of disease etiology, and more efficient therapeutic strategies.1Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Technische Universität München, Munich, Germany.Baiba Vilne 1,2 and Heribert Schunkert 1,2 * ![]()
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